Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GLIS2 Antibody (Center) Blocking Peptide   

GLIS2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BZE0
Clone Names 100603202
Peptide ID 100603202
Additional Information
Gene ID 84662
Other Names Zinc finger protein GLIS2, GLI-similar 2, Neuronal Krueppel-like protein, GLIS2, NKL
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLIS2
Synonyms NKL
Function Can act either as a transcriptional repressor or as a transcriptional activator, depending on the cell context. Acts as a repressor of the Hedgehog signaling pathway (By similarity). Represses the Hedgehog-dependent expression of Wnt4 (By similarity). Necessary to maintain the differentiated epithelial phenotype in renal cells through the inhibition of SNAI1, which itself induces the epithelial-to-mesenchymal transition (By similarity). Represses transcriptional activation mediated by CTNNB1 in the Wnt signaling pathway. May act by recruiting the corepressors CTBP1 and HDAC3. May be involved in neuron differentiation (By similarity).
Cellular Location Nucleus speckle. Cytoplasm
Tissue Location Expressed at high levels in kidney and at low levels in heart, lung and placenta. Expressed in colon
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


This gene is a member of the GLI-similar zinc fingerprotein family and encodes a nuclear transcription factor with fiveC2H2-type zinc finger domains. The protein encoded by this gene iswidely expressed at low levels in the neural tube and peripheralnervous system and likely promotes neuronal differentiation. It isabundantly expressed in the kidney and may have a role in theregulation of kidney morphogenesis. p120 regulates the expressionlevel of this protein and induces the cleavage of this protein'sC-terminal zinc finger domain. This protein also promotes thenuclear translocation of p120. Mutations in this gene causenephronophthisis (NPHP), an autosomal recessive kidney diseasecharacterized by tubular basement membrane disruption, interstitiallymphohistiocytic cell infiltration, and development of cysts atthe corticomedullary border of the kidneys.


Attanasio, M., et al. Nat. Genet. 39(8):1018-1024(2007)Hosking, C.R., et al. Mol. Biol. Cell 18(5):1918-1927(2007)Kim, Y.S., et al. FEBS Lett. 581(5):858-864(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Kim, Y.S., et al. Nucleic Acids Res. 31(19):5513-5525(2003)

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

$ 80.00
Cat# BP16510c
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
“Crown Flash”  50 % off on 2,500+ Crown Antibodies. PromoCode:<span class=text-red> FLASH50
Terms & Conditions