ACCN4 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96FT7 |
---|---|
Clone Names | 100603256 |
Gene ID | 55515 |
---|---|
Other Names | Acid-sensing ion channel 4, ASIC4, Amiloride-sensitive cation channel 4, Amiloride-sensitive cation channel 4, pituitary, ASIC4, ACCN4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ASIC4 |
---|---|
Synonyms | ACCN4 |
Function | Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. |
Cellular Location | Membrane; Multi-pass membrane protein |
Tissue Location | Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to the superfamily of acid-sensing ionchannels, which are proton-gated, amiloride-sensitive sodiumchannels. These channels have been implicated in synaptictransmission, pain perception as well as mechanoperception. Thisgene is predominantly expressed in the pituitary gland, and wasconsidered a candidate for paroxysmal dystonic choreoathetosis(PDC), a movement disorder, however, no correlation was foundbetween mutations in this gene and PDC. Alternative splicing atthis locus results in two transcript variants encoding differentisoforms.
References
Donier, E., et al. Eur. J. Neurosci. 28(1):74-86(2008)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hillier, L.W., et al. Nature 434(7034):724-731(2005)Grunder, S., et al. Eur. J. Hum. Genet. 9(9):672-676(2001)Grunder, S., et al. Neuroreport 11(8):1607-1611(2000)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.