|Other Names||Trace amine-associated receptor 8, TaR-8, Trace amine receptor 8, G-protein coupled receptor 102, Trace amine receptor 5, TaR-5, TAAR8, GPR102, TA5, TAR5, TRAR5|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||GPR102, TA5, TAR5, TRAR5|
|Function||Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested|
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Provided below are standard protocols that you may find useful for product applications.
G protein-coupled receptors (GPCRs, or GPRs) contain 7transmembrane domains and transduce extracellular signals throughheterotrimeric G proteins.
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)Liberles, S.D., et al. Nature 442(7103):645-650(2006)Lewin, A.H. AAPS J 8 (1), E138-E145 (2006) :Lindemann, L., et al. Genomics 85(3):372-385(2005)Mungall, A.J., et al. Nature 425(6960):805-811(2003)
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