SLITRK4 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IW52 |
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Clone Names | 100617039 |
Gene ID | 139065 |
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Other Names | SLIT and NTRK-like protein 4, SLITRK4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SLITRK4 |
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Function | It is involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321). Suppresses neurite outgrowth (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein. Cell membrane |
Tissue Location | Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a transmembrane protein belonging to thethe SLITRK family. These family members include two N-terminalleucine-rich repeat domains similar to those found in the axonalgrowth-controlling protein SLIT, as well as C-terminal regionssimilar to neurotrophin receptors. Studies of an homologous proteinin mouse suggest that this family member functions to suppressneurite outgrowth. Alternative splicing results in multipletranscript variants.
References
Aruga, J., et al. Gene 315, 87-94 (2003) :Aruga, J., et al. Mol. Cell. Neurosci. 24(1):117-129(2003)
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