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SLITRK4 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8IW52
Clone Names 100617039
Additional Information
Gene ID 139065
Other Names SLIT and NTRK-like protein 4, SLITRK4
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLITRK4
Function It is involved in synaptogenesis and promotes synapse differentiation (PubMed:27812321). Suppresses neurite outgrowth (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein. Cell membrane
Tissue Location Expressed in the cerebral cortex of the brain and at higher levels in some astrocytic brain tumors such as astrocytomas, glioblastomas and primitive neuroectodermal tumors
Research Areas
Citations (0)
citation

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Background

This gene encodes a transmembrane protein belonging to thethe SLITRK family. These family members include two N-terminalleucine-rich repeat domains similar to those found in the axonalgrowth-controlling protein SLIT, as well as C-terminal regionssimilar to neurotrophin receptors. Studies of an homologous proteinin mouse suggest that this family member functions to suppressneurite outgrowth. Alternative splicing results in multipletranscript variants.

References

Aruga, J., et al. Gene 315, 87-94 (2003) :Aruga, J., et al. Mol. Cell. Neurosci. 24(1):117-129(2003)

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$ 277.78
Cat# BP16537b
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