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MTMR6 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y217
Clone Names 100617179
Peptide ID 100617179
Additional Information
Gene ID 9107
Other Names Myotubularin-related protein 6, 313-, MTMR6
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTMR6
Function Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.
Cellular Location Nucleus envelope
Tissue Location Expressed in CD4+ T-cells.
Research Areas
Citations (0)

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Background

Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells.

References

Zou, J., et al. J. Biol. Chem. 284(4):2064-2071(2009)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)Srivastava, S., et al. Mol. Cell. Biol. 26(15):5595-5602(2006)Srivastava, S., et al. Mol. Cell. Biol. 25(9):3630-3638(2005)

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$ 80.00
Cat# BP16543a
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