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RIT2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q99578 |
|---|---|
| Clone Names | 100603068 |
| Gene ID | 6014 |
|---|---|
| Other Names | GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2, RIT2, RIN, ROC2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RIT2 |
|---|---|
| Synonyms | RIN, ROC2 |
| Function | Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator. |
| Cellular Location | Nucleus. Cell membrane. Note=Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393). |
| Tissue Location | Neuron-specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RIN belongs to the RAS (HRAS; MIM 190020) superfamily ofsmall GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied byOMIM].
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010)Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :Wu, C., et al. Proteomics 7(11):1775-1785(2007)
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