|Other Names||GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2, RIT2, RIN, ROC2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.|
|Cellular Location||Nucleus. Cell membrane. Note=Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).|
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Provided below are standard protocols that you may find useful for product applications.
RIN belongs to the RAS (HRAS; MIM 190020) superfamily ofsmall GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied byOMIM].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010)Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :Wu, C., et al. Proteomics 7(11):1775-1785(2007)
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