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RIT2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q99578
Clone Names 100603068
Peptide ID 100603068
Additional Information
Gene ID 6014
Other Names GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2, RIT2, RIN, ROC2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIT2
Synonyms RIN, ROC2
Function Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
Cellular Location Nucleus. Cell membrane. Note=Colocalizes with PLXNB3 at the plasma membrane. {ECO:0000250|UniProtKB:Q99578}
Tissue Location Neuron-specific.
Research Areas
Citations (0)

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Background

RIN belongs to the RAS (HRAS; MIM 190020) superfamily ofsmall GTPases (Shao et al., 1999 [PubMed 10545207]).[supplied byOMIM].

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010)Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :Wu, C., et al. Proteomics 7(11):1775-1785(2007)

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$ 80.00
Cat# BP16551a
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