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EDEM3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BZQ6
Clone Names 100603100
Peptide ID 100603100
Additional Information
Gene ID 80267
Other Names ER degradation-enhancing alpha-mannosidase-like protein 3, Alpha-1, 2-mannosidase EDEM3, EDEM3, C1orf22
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDEM3
Synonyms C1orf22
Function Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity (By similarity).
Cellular Location Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}
Research Areas
Citations (0)

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Quality control in the endoplasmic reticulum (ER) ensuresthat only properly folded proteins are retained in the cell throughrecognition and degradation of misfolded or unassembled proteins.EDEM3 belongs to a group of proteins that accelerate degradation ofmisfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed16431915]).


Hirao, K., et al. J. Biol. Chem. 281(14):9650-9658(2006)Mast, S.W., et al. Glycobiology 15(4):421-436(2005)Olivari, S., et al. J. Biol. Chem. 280(4):2424-2428(2005)Sood, R., et al. Genomics 73(2):211-222(2001)

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$ 80.00
Cat# BP16556b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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