|Other Names||DNA repair protein RAD52 homolog, RAD52|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.|
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The protein encoded by this gene shares similarity withSaccharomyces cerevisiae Rad52, a protein important for DNAdouble-strand break repair and homologous recombination. This geneproduct was shown to bind single-stranded DNA ends, and mediate theDNA-DNA interaction necessary for the annealing of complementaryDNA strands. It was also found to interact with DNA recombinationprotein RAD51, which suggested its role in RAD51 related DNArecombination and repair.
Liu, Y., et al. Carcinogenesis 31(10):1762-1769(2010)Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
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