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SEL1L Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9UBV2
Clone Names 100318056
Additional Information
Gene ID 6400
Other Names Protein sel-1 homolog 1, Suppressor of lin-12-like protein 1, Sel-1L, SEL1L, TSA305
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEL1L
Synonyms TSA305
Function Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:16186509, PubMed:29997207). Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in pancreas.
Research Areas
Citations (0)
citation

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Background

SEL1L may play a role in Notch signaling (By similarity). May be involved in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.

References

Ban, H.J., et al. BMC Genet. 11, 26 (2010) :Riemer, J., et al. Proc. Natl. Acad. Sci. U.S.A. 106(35):14831-14836(2009)Cormier, J.H., et al. Mol. Cell 34(5):627-633(2009)Oresic, K., et al. Biosci. Rep. 29(3):173-181(2009)Cattaneo, M., et al. J. Biol. Chem. 284(17):11405-11415(2009)

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$ 277.78
Cat# BP16575a
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