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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   NKX6-1 Antibody (C-term) Blocking Peptide   

NKX6-1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P78426
Clone Names 100406294
Peptide ID 100406294
Additional Information
Gene ID 4825
Other Names Homeobox protein Nkx-61, Homeobox protein NK-6 homolog A, NKX6-1, NKX6A
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NKX6-1
Synonyms NKX6A
Function Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes. Involved in transcriptional regulation in islet beta cells. Binds to the insulin promoter and is involved in regulation of the insulin gene. Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).
Cellular Location Nucleus.
Tissue Location Pancreatic beta cells.
Research Areas
Citations (0)

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In the pancreas, NKX6.1 is required for the development ofbeta cells and is a potent bifunctional transcription regulatorthat binds to AT-rich sequences within the promoter region oftarget genes Iype et al. (2004) [PubMed 15056733].[supplied byOMIM].


Donelan, W., et al. J. Biol. Chem. 285(16):12181-12189(2010)Zhu, S., et al. Dig. Dis. Sci. 54(5):996-1002(2009)Schisler, J.C., et al. Mol. Cell. Biol. 28(10):3465-3476(2008)Yokoi, N., et al. Diabetes 55(8):2379-2386(2006)Hori, Y., et al. PLoS Med. 2 (4), E103 (2005) :

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$ 80.00
Cat# BP16589b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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