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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   KATNB1 Antibody (Center) Blocking Peptide   

KATNB1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9BVA0
Clone Names 100528255
Peptide ID 100528255
Additional Information
Gene ID 10300
Other Names Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022}, KATNB1 {ECO:0000255|HAMAP-Rule:MF_03022}
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name KATNB1 {ECO:0000255|HAMAP-Rule:MF_03022}
Function Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton Note=Predominantly cytoplasmic. Localized to the interphase centrosome and mitotic spindle poles
Research Areas
Citations (0)

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Microtubules, polymers of alpha and beta tubulin subunits,form the mitotic spindle of a dividing cell and help to organizemembranous organelles during interphase. Katanin is a heterodimerthat consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDaaccessory protein (p80 subunit B 1). The p60 subunit acts to severand disassemble microtubules, while the p80 subunit targets theenzyme to the centrosome. Katanin is a member of the AAA family ofATPases.


Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :Cummings, C.M., et al. J. Biol. Chem. 284(17):11663-11675(2009)Sudo, H., et al. Hum. Mol. Genet. 17(16):2524-2540(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP16597c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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