|Other Names||Syntenin-2, Syndecan-binding protein 2, SDCBP2, SITAC18|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)Deloukas, P., et al. Nature 414(6866):865-871(2001)Koroll, M., et al. J. Biol. Chem. 276(14):10646-10654(2001)Borrell-Pages, M., et al. Mol. Biol. Cell 11(12):4217-4225(2000)
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