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ISG20 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96AZ6
Clone Names 100603108
Peptide ID 100603108
Additional Information
Gene ID 3669
Other Names Interferon-stimulated gene 20 kDa protein, Estrogen-regulated transcript 45 protein, Promyelocytic leukemia nuclear body-associated protein ISG20, ISG20, HEM45
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ISG20
Synonyms HEM45
Function Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single- stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis.
Cellular Location Nucleus. Nucleus, nucleolus. Cytoplasm. Nucleus, Cajal body
Tissue Location Highly expressed in peripheral blood leukocytes, spleen, thymus, colon and lung. Up regulated by E2 in estrogen receptor-positive breast cancer lines
Research Areas
Citations (0)

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Exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. Degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. Involved in the antiviral function of IFN against RNA viruses.


Hao, Y., et al. J. Huazhong Univ. Sci. Technol. Med. Sci. 28(1):11-13(2008)Horio, T., et al. FEBS Lett. 577 (1-2), 111-116 (2004) :Espert, L., et al. J. Biol. Chem. 278(18):16151-16158(2003)Izmailova, E., et al. Nat. Med. 9(2):191-197(2003)Nguyen, L.H., et al. Biochemistry 40(24):7174-7179(2001)

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$ 80.00
Cat# BP16602c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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