|Other Names||Mast cell-expressed membrane protein 1, MCEMP1, C19orf59|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed specifically in mast cells. Found primarily in lung. EMBL; AF461155; AAO15597.1; -; mRNA EMBL; AF461156; AAO15598.1; -; mRNA EMBL; AC008763; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC104796; AAI04797.1; -; mRNA EMBL; BC104798; AAI04799.1; -; mRNA CCDS; CCDS12183.1; - RefSeq; NP_777578.2; NM_174918.2 UniGene; Hs.709539; - ProteinModelPortal; Q8IX19; - BioGrid; 128261; 1 IntAct; Q8IX19; 7 iPTMnet; Q8IX19; - PhosphoSitePlus; Q8IX19; - BioMuta; MCEMP1; - DMDM; 74759647; - PaxDb; Q8IX19; - PeptideAtlas; Q8IX19; - PRIDE; Q8IX19; - Ensembl; ENST00000333598; ENSP00000329920; ENSG00000183019 GeneID; 199675; - KEGG; hsa:199675; - UCSC; uc002mhh.2; human CTD; 199675; - GeneCards; MCEMP1; - HGNC; HGNC:27291; MCEMP1 HPA; HPA014731; - MIM; 609565; gene neXtProt; NX_Q8IX19; - OpenTargets; ENSG00000183019; - PharmGKB; PA162378700; - eggNOG; ENOG410JDQ4; Eukaryota eggNOG; ENOG41119J7; LUCA GeneTree; ENSGT00390000007959; - HOGENOM; HOG000113496; - HOVERGEN; HBG071355; - InParanoid; Q8IX19; - OMA; VEEIYKH; - OrthoDB; EOG091G0TQV; - PhylomeDB; Q8IX19; - TreeFam; TF337063; - BioCyc; ZFISH:G66-31045-MONOMER; - Reactome; R-HSA-6798695; Neutrophil degranulation GenomeRNAi; 199675; - PRO; PR:Q8IX19; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000183019; - CleanEx; HS_C19orf59; - ExpressionAtlas; Q8IX19; baseline and differential Genevisible; Q8IX19; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW 1: Evidence at protein level; Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix CHAIN 1 187 Mast cell-expressed membrane protein 1 /FTId=PRO_0000274052 TOPO_DOM 1 85 Cytoplasmic. TRANSMEM 86 106 Helical; Signal-anchor for type II membrane protein. TOPO_DOM 107 187 Extracellular. CARBOHYD 124 124 N-linked (GlcNAc...). VARIANT 129 129 V -> I (in dbSNP:rs8111596) /FTId=VAR_059697 VARIANT 167 167 I -> V (in dbSNP:rs72996468) /FTId=VAR_030180 VARIANT 175 175 L -> V (in dbSNP:rs10409343) /FTId=VAR_051159 SEQUENCE 187 AA; 21229 MW; E7D910214BF6BDD3 CRC64; MEVEEIYKHQ EVKMQAPAFR DKKQGVSAKN QGAHDPDYEN ITLAFKNQDH AKGGHSRPTS QVPAQCRPPS DSTQVPCWLY RAILSLYILL ALAFVLCIIL SAFIMVKNAE MSKELLGFKR ELWNVSNSVQ ACEERQKRGW DSVQQSITMV RSKIDRLETT LAGIKNIDTK VQKILEVLQK MPQSSPQ|
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This gene encodes a single-pass transmembrane protein.Based on its expression pattern, it is speculated to be involved inregulating mast cell differentiation or immune responses.
Li, K., et al. Genomics 86(1):68-75(2005)
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