|Other Names||Equatorin, Acrosome formation-associated factor, EQTN, AFAF, C9orf11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Single-pass type I membrane protein. Note=In the anterior acrosome region, enriched on the inner acrosomal membrane but minimal on the outer acrosomal membrane; in contrast in the posterior acrosome region enriched on both the inner and outer acrosomal membranes|
|Tissue Location||Isoform 1 is highly expressed in testis. Isoform 2 is expressed at low levels in skin and blood|
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Provided below are standard protocols that you may find useful for product applications.
AFAF is involved in acrosome biogenesis (By similarity).
Laaksovirta, H., et al. Lancet Neurol 9(10):978-985(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Li, Y.C., et al. FEBS Lett. 580(17):4266-4273(2006)Ruiz, A., et al. Biochim. Biophys. Acta 1517(1):128-134(2000)
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