|Other Names||Signal recognition particle 54 kDa protein, SRP54, SRP54|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).|
|Cellular Location||Nucleus speckle. Cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
SRP54 binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).
Rose, J. Phd, et al. Mol. Med. (2010) In press :Yoshida, M., et al. Mol. Pharmacol. 73(3):987-994(2008)Sakashita, E., et al. Mol. Cell. Biol. 24(3):1174-1187(2004)Kuglstatter, A., et al. Nat. Struct. Biol. 9(10):740-744(2002)Yin, J., et al. RNA 7(10):1389-1396(2001)
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