|Other Names||G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.|
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Provided below are standard protocols that you may find useful for product applications.
G protein-coupled receptors play a role in cellcommunication. They are characterized by an extracellular Nterminus, 7 transmembrane regions, and an intracellular Cterminus.
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Zhang, Y., et al. Cancer Res. 69(15):6049-6056(2009)Glatt, S., et al. Int. J. Cancer 122(9):2008-2016(2008)Gugger, M., et al. Dis. Markers 24(1):41-50(2008)Tabata, K., et al. Biochem. Biophys. Res. Commun. 363(3):861-866(2007)
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