GPR87 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BY21 |
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Clone Names | 100603166 |
Gene ID | 53836 |
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Other Names | G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GPR87 |
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Synonyms | GPR95 |
Function | Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
G protein-coupled receptors play a role in cellcommunication. They are characterized by an extracellular Nterminus, 7 transmembrane regions, and an intracellular Cterminus.
References
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Zhang, Y., et al. Cancer Res. 69(15):6049-6056(2009)Glatt, S., et al. Int. J. Cancer 122(9):2008-2016(2008)Gugger, M., et al. Dis. Markers 24(1):41-50(2008)Tabata, K., et al. Biochem. Biophys. Res. Commun. 363(3):861-866(2007)
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