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RYBP Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8N488
Clone Names 100528285
Peptide ID 100528285
Additional Information
Gene ID 23429
Other Names RING1 and YY1-binding protein, Apoptin-associating protein 1, APAP-1, Death effector domain-associated factor, DED-associated factor, YY1 and E4TF1-associated factor 1, RYBP, DEDAF, YEAF1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DEDAF, YEAF1
Function Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.
Cellular Location Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Primarily found in the nucleus. Detected in a punctate pattern likely to represent Polycomb group (PcG) bodies (By similarity).
Tissue Location Widely expressed with highest levels in lymphoid tissues and placenta.
Research Areas
Citations (0)

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RYBP may be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. In tumor cell lines, may induce apoptosis.


Rose, J. Phd, et al. Mol. Med. (2010) In press :Chen, D., et al. EMBO Rep. 10(2):166-172(2009)Novak, R.L., et al. Cancer Gene Ther. 15(11):713-722(2008)Danen-van Oorschot, A.A., et al. Cell Death Differ. 11(5):564-573(2004)Guelen, L., et al. Oncogene 23(5):1153-1165(2004)

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$ 80.00
Cat# BP16629a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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