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SOX8 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P57073 |
|---|---|
| Clone Names | 100528305 |
| Gene ID | 30812 |
|---|---|
| Other Names | Transcription factor SOX-8, SOX8 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SOX8 {ECO:0000303|Ref.1, ECO:0000312|HGNC:HGNC:11203} |
|---|---|
| Function | Transcription factor that may play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the SOX (SRY-relatedHMG-box) family of transcription factors involved in the regulationof embryonic development and in the determination of the cell fate.The encoded protein may act as a transcriptional activator afterforming a protein complex with other proteins. This protein may beinvolved in brain development and function. Haploinsufficiency forthis protein may contribute to the mental retardation found inhaemoglobin H-related mental retardation (ART-16 syndrome).
References
Nonaka, D. Am. J. Clin. Pathol. 131(5):731-736(2009)Hoff, S., et al. J. Comp. Neurol. 509(4):356-371(2008)Wissmuller, S., et al. Nucleic Acids Res. 34(6):1735-1744(2006)Schepers, G., et al. J. Biol. Chem. 278(30):28101-28108(2003)Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
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