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NHLH2 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q02577
Clone Names 100603117
Peptide ID 100603117
Additional Information
Other Names Helix-loop-helix protein 2, HEN-2, Class A basic helix-loop-helix protein 34, bHLHa34, Nescient helix loop helix 2, NSCL-2, NHLH2, BHLHA34, HEN2, KIAA0490
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NHLH2
Synonyms BHLHA34, HEN2, KIAA0490
Function May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981} EMBL; M97508; AAA58635.1; -; Genomic_DNA EMBL; AB007959; -; NOT_ANNOTATED_CDS; mRNA EMBL; AL449264; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC096359; AAH96359.1; -; mRNA EMBL; BC096360; AAH96360.1; -; mRNA CCDS; CCDS885.1; - PIR; B45075; B45075 RefSeq; NP_001104531.1; NM_001111061.1 RefSeq; NP_005590.1; NM_005599.3 UniGene; Hs.46296; - ProteinModelPortal; Q02577; - SMR; Q02577; - BioGrid; 110873; 15 CORUM; Q02577; - IntAct; Q02577; 6 STRING; 9606.ENSP00000322087; - iPTMnet; Q02577; - PhosphoSitePlus; Q02577; - BioMuta; NHLH2; - DMDM; 399887; - PaxDb; Q02577; - PeptideAtlas; Q02577; - PRIDE; Q02577; - ProteomicsDB; 58112; - DNASU; 4808; - Ensembl; ENST00000320238; ENSP00000322087; ENSG00000177551 Ensembl; ENST00000369506; ENSP00000358519; ENSG00000177551 GeneID; 4808; - KEGG; hsa:4808; - UCSC; uc001efy.4; human CTD; 4808; - DisGeNET; 4808; - EuPathDB; HostDB:ENSG00000177551.5; - GeneCards; NHLH2; - HGNC; HGNC:7818; NHLH2 HPA; HPA055238; - MIM; 162361; gene neXtProt; NX_Q02577; - OpenTargets; ENSG00000177551; - PharmGKB; PA31620; - eggNOG; KOG4029; Eukaryota eggNOG; ENOG411227D; LUCA GeneTree; ENSGT00760000119097; - HOGENOM; HOG000016617; - HOVERGEN; HBG016345; - InParanoid; Q02577; - KO; K09075; - OMA; ATLYPHP; - OrthoDB; EOG091G0RR2; - PhylomeDB; Q02577; - SIGNOR; Q02577; - GenomeRNAi; 4808; - PRO; PR:Q02577; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000177551; - CleanEx; HS_NHLH2; - ExpressionAtlas; Q02577; baseline and differential Genevisible; Q02577; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0005667; C:transcription factor complex; TAS:BHF-UCL GO; GO:0046983; F:protein dimerization activity; IEA:InterPro GO; GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:BHF-UCL GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IBA:GO_Central GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001077; F:transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW GO; GO:0007417; P:central nervous system development; TAS:ProtInc GO; GO:0007617; P:mating behavior; IEA:Ensembl GO; GO:0042698; P:ovulation cycle; IEA:Ensembl GO; GO:0051091; P:positive regulation of DNA binding transcription factor activity; TAS:BHF-UCL GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; TAS:BHF-UCL CDD; cd00083; HLH; 1 Gene3D; 4.10.280.10; -; 1 InterPro; IPR011598; bHLH_dom InterPro; IPR036638; HLH_DNA-bd_sf Pfam; PF00010; HLH; 1 SMART; SM00353; HLH; 1 SUPFAM; SSF47459; SSF47459; 1 PROSITE; PS50888; BHLH; 1 1: Evidence at protein level; Complete proteome; Developmental protein; Differentiation; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation CHAIN 1 135 Helix-loop-helix protein 2 /FTId=PRO_0000127199 DOMAIN 77 129 bHLH. {ECO:0000255|PROSITE- ProRule:PRU00981} COMPBIAS 69 73 Poly-Arg SEQUENCE 135 AA; 15018 MW; 083730499F610AAE CRC64; MMLSPDQAAD SDHPSSAHSD PESLGGTDTK VLGSVSDLEP VEEAEGDGKG GSRAALYPHP QQLSREEKRR RRRATAKYRS AHATRERIRV EAFNLAFAEL RKLLPTLPPD KKLSKIEILR LAICYISYLN HVLDV
Research Areas
Citations (0)

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Background

NHLH2 may serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

References

Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)Good, D.J., et al. Exerc Sport Sci Rev 36(4):187-192(2008)Aoyama, M., et al. Cancer Res. 65(11):4587-4597(2005)Lipkowitz, S., et al. J. Biol. Chem. 267(29):21065-21071(1992)Brown, L., et al. Proc. Natl. Acad. Sci. U.S.A. 89(18):8492-8496(1992)

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$ 80.00
Cat# BP16640c
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