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IRX5 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P78411 |
|---|---|
| Clone Names | 100617006 |
| Gene ID | 10265 |
|---|---|
| Other Names | Iroquois-class homeodomain protein IRX-5, Homeodomain protein IRX-2A, Homeodomain protein IRXB2, Iroquois homeobox protein 5, IRX5, IRX2A, IRXB2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IRX5 |
|---|---|
| Synonyms | IRX2A, IRXB2 |
| Function | Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells. Involved in craniofacial and gonadal development. Modulates the migration of progenitor cell populations in branchial arches and gonads by repressing CXCL12. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
IRX5 is a member of the Iroquois homeobox gene family.Members of this family appear to play multiple roles during patternformation of vertebrate embryos.
References
Myrthue, A., et al. Clin. Cancer Res. 14(11):3562-3570(2008)Bruneau, B.G. Med Sci (Paris) 22(3):231-232(2006)Ogura, K., et al. Cytogenet. Cell Genet. 92 (3-4), 320-325 (2001) :Lewis, M.T., et al. Cell Tissue Res. 296(3):549-554(1999)
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