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ZBTB38 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NAP3
Clone Names 100603004
Peptide ID 100603004
Additional Information
Gene ID 253461
Other Names Zinc finger and BTB domain-containing protein 38, ZBTB38 (HGNC:26636)
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB38 (HGNC:26636)
Function Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl- CpG-dependent manner (PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA- replication (PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons (By similarity).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters.
Research Areas
Citations (0)

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The protein encoded by this gene is a zinc fingertranscriptional activator that binds methylated DNA. The encodedprotein can form homodimers or heterodimers through the zinc fingerdomains. In mouse, inhibition of this protein has been associatedwith apoptosis in some cell types.


Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)Kim, J.J., et al. J. Hum. Genet. 55(1):27-31(2010)Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :Cho, Y.S., et al. Nat. Genet. 41(5):527-534(2009)Soranzo, N., et al. PLoS Genet. 5 (4), E1000445 (2009) :

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$ 80.00
Cat# BP16697a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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