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SNX15 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9NRS6
Clone Names 100603111
Additional Information
Gene ID 29907
Other Names Sorting nexin-15, SNX15
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNX15
Function May be involved in several stages of intracellular trafficking. Overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the TGN.
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the sorting nexin family.Members of this family contain a phox (PX) domain, which is aphosphoinositide binding domain, and are involved in intracellulartrafficking. Overexpression of this gene results in a decrease inthe processing of insulin and hepatocyte growth factor receptors totheir mature subunits. This decrease is caused by themislocalization of furin, the endoprotease responsible for cleavageof insulin and hepatocyte growth factor receptors. This protein isinvolved in endosomal trafficking from the plasma membrane torecycling endosomes or the trans-Golgi network. This gene encodestwo transcript variants encoding distinct isoforms. [provided byRefSeq].

References

Venter, J.C., et al. Science 291(5507):1304-1351(2001)Phillips, S.A., et al. J. Biol. Chem. 276(7):5074-5084(2001)Barr, V.A., et al. Traffic 1(11):904-916(2000)

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$ 277.78
Cat# BP16711b
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