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ACOX2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q99424
Clone Names 100603291
Additional Information
Gene ID 8309
Other Names Peroxisomal acyl-coenzyme A oxidase 2, 3-alpha, 7-alpha, 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 3-alpha, 7-alpha, 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, Trihydroxycoprostanoyl-CoA oxidase, THCA-CoA oxidase, THCCox, ACOX2
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACOX2 (HGNC:120)
Function Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids (PubMed:27884763). Capable of oxidizing short as well as long chain 2-methyl branched fatty acids (By similarity).
Cellular Location Peroxisome
Tissue Location Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
Research Areas
Citations (0)
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Background

The product of this gene belongs to the acyl-CoA oxidasefamily. It encodes the branched-chain acyl-CoA oxidase which isinvolved in the degradation of long branched fatty acids and bileacid intermediates in peroxisomes. Deficiency of this enzymeresults in the accumulation of branched fatty acids and bile acidintermediates, and may lead to Zellweger syndrome, severe mentalretardation, and death in children.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Rikova, K., et al. Cell 131(6):1190-1203(2007)Wanders, R.J., et al. Annu. Rev. Biochem. 75, 295-332 (2006) :Moghrabi, N.N., et al. Biochem. Biophys. Res. Commun. 231(3):767-769(1997)Baumgart, E., et al. Ann. N. Y. Acad. Sci. 804, 678-679 (1996) :

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$ 277.78
Cat# BP16717a
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