|Other Names||Bifunctional apoptosis regulator, RING finger protein 47, BFAR, BAR, RNF47|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.|
|Cellular Location||Endoplasmic reticulum membrane; Multi- pass membrane protein|
|Tissue Location||Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen|
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Provided below are standard protocols that you may find useful for product applications.
BFAR is a apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
Liu, X., et al. Retina (Philadelphia, Pa.) (2010) In press :Chua, C.C., et al. Cardiovasc. Res. 81(1):20-27(2009)Roth, W., et al. Cell Death Differ. 10(10):1178-1187(2003)Zhang, H., et al. Proc. Natl. Acad. Sci. U.S.A. 97(6):2597-2602(2000)
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