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OR1D2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P34982 |
|---|---|
| Clone Names | 110617048 |
| Gene ID | 4991 |
|---|---|
| Other Names | Olfactory receptor 1D2, Olfactory receptor 17-4, OR17-4, Olfactory receptor OR17-6, Olfactory receptor-like protein HGMP07E, OR1D2, OLFR1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OR1D2 |
|---|---|
| Synonyms | OLFR1 |
| Function | Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Note=In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal |
| Tissue Location | Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Olfactory receptors interact with odorant molecules in thenose, to initiate a neuronal response that triggers the perceptionof a smell. The olfactory receptor proteins are members of a largefamily of G-protein-coupled receptors (GPCR) arising from singlecoding-exon genes. Olfactory receptors share a 7-transmembranedomain structure with many neurotransmitter and hormone receptorsand are responsible for the recognition and G protein-mediatedtransduction of odorant signals. The olfactory receptor gene familyis the largest in the genome. The nomenclature assigned to theolfactory receptor genes and proteins for this organism isindependent of other organisms.
References
Neuhaus, E.M., et al. J. Cell. Sci. 119 (PT 15), 3047-3056 (2006) :Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)Spehr, M., et al. Science 299(5615):2054-2058(2003)Fuchs, T., et al. Genomics 80(3):295-302(2002)Glusman, G., et al. Genomics 63(2):227-245(2000)
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