|Other Names||Endoplasmic reticulum-Golgi intermediate compartment protein 2, ERGIC2, ERV41, PTX1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Possible role in transport between endoplasmic reticulum and Golgi.|
|Cellular Location||Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Note=Cycles between the endoplasmic reticulum and the Golgi. According to a report, localizes to the nucleus (PubMed:11445006). Another report shows a partial localization in the nucleus (PubMed:17980171)|
|Tissue Location||Ubiquitously expressed.|
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ERGIC2, or PTX1, is a ubiquitously expressed nuclearprotein that is downregulated in prostate carcinoma (Kwok et al.,2001 [PubMed 11445006]).
Yang, Y.F., et al. Biochim. Biophys. Acta 1784(2):312-318(2008)Kwok, S.C., et al. DNA Cell Biol. 25(9):523-529(2006)Breuza, L., et al. J. Biol. Chem. 279(45):47242-47253(2004)Liu, X., et al. DNA Cell Biol. 22(7):469-474(2003)Kwok, S.C., et al. DNA Cell Biol. 20(6):349-357(2001)
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