Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
RFX1 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P22670 |
|---|---|
| Clone Names | 100318008 |
| Gene ID | 5989 |
|---|---|
| Other Names | MHC class II regulatory factor RFX1, Enhancer factor C, EF-C, Regulatory factor X 1, RFX, Transcription factor RFX1, RFX1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RFX1 |
|---|---|
| Function | Regulatory factor essential for MHC class II genes expression. Binds to the X boxes of MHC class II genes. Also binds to an inverted repeat (ENH1) required for hepatitis B virus genes expression and to the most upstream element (alpha) of the RPL30 promoter. |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the regulatory factor X genefamily, which encodes transcription factors that contain ahighly-conserved winged helix DNA binding domain. The proteinencoded by this gene is structurally related to regulatory factorsX2, X3, X4, and X5. It is a transcriptional activator that can bindDNA as a monomer or as a heterodimer with RFX family members X2,X3, and X5, but not with X4. This protein binds to the X-boxes ofMHC class II genes and is essential for their expression. Also, itcan bind to an inverted repeat that is required for expression ofhepatitis B virus genes.
References
Zhao, M., et al. J. Autoimmun. 35(1):58-69(2010)Purvis, T.L., et al. Gene 460 (1-2), 20-29 (2010) :Hsu, Y.C., et al. J. Biol. Chem. 285(18):13885-13895(2010)Seguin-Estevez, Q., et al. J. Immunol. 183(4):2545-2553(2009)Zhang, Y., et al. Mol. Biol. (Mosk.) 43(1):77-84(2009)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
