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DSC3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14574
Clone Names 100528058
Peptide ID 100528058
Additional Information
Gene ID 1825
Other Names Desmocollin-3, Cadherin family member 3, Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DSC3
Synonyms CDHF3, DSC4
Function Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
Cellular Location Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
Tissue Location Epidermis, buccal mucosa, esophagus and cervix
Research Areas
Citations (0)

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The protein encoded by this gene is a calcium-dependentglycoprotein that is a member of the desmocollin subfamily of thecadherin superfamily. These desmosomal family members, along withthe desmogleins, are found primarily in epithelial cells where theyconstitute the adhesive proteins of the desmosome cell-celljunction and are required for cell adhesion and desmosomeformation. The desmosomal family members are arranged in twoclusters on chromosome 18, occupying less than 650 kb combined.Alternative splicing results in two transcript variants encodingdistinct isoforms.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :Spindler, V., et al. J. Biol. Chem. 284(44):30556-30564(2009)Ayub, M., et al. Am. J. Hum. Genet. 85(4):515-520(2009)Aoyama, Y., et al. Exp. Dermatol. 18(4):404-408(2009)

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$ 80.00
Cat# BP16771b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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