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EAN57 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O43247 |
|---|---|
| Clone Names | 100422255 |
| Gene ID | 339669 |
|---|---|
| Other Names | Testis-expressed sequence 33 protein, TEX33, C22orf33, EAN57 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CIMIP4 (HGNC:28568) |
|---|---|
| Synonyms | C22orf33, EAN57, TEX33 |
| Function | Seems to be associated with spermiogenesis but is not essential for sperm development and male fertility. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250|UniProtKB:Q9D9J2}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9D9J2} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
EAN57 is a 59 amino acid protein encoded by the C22orf33 protein. Chromosome 22 contains over 500 genes and about 49 million bases. Being the second smallest human chromosome, 22 contains a surprising variety of interesting genes. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein, BCR-Abl, a potent cell proliferation activator found in several types of leukemia.
References
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
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