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C18orf26 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8N1N2
Clone Names 100422292
Peptide ID 100422292
Additional Information
Gene ID 284254
Other Names Dynactin-associated protein, Full, DYNAP, C18orf26
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name DYNAP
Synonyms C18orf26
Function Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'.
Cellular Location Golgi apparatus membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note=Concentrated at cell-cell borders. Localizes at membranes in a microtubule-dependent manner
Tissue Location Expressed in fibroblast and numerous cancer cell lines (at protein level).
Research Areas
Citations (0)

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Background

C18orf26 (chromosome 18 open reading frame 26) is a 210 amino acid single pass membrane protein that is encoded by a gene which maps to human chromosome 18. Chromosome 18 houses over 300 protein-coding genes and contains nearly 76 million nucleotide bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

References

Kunoh, T., et al. Mol. Cancer Ther. 9(11):2934-2942(2010)

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$ 80.00
Cat# BP16785a
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