|Other Names||Condensin-2 complex subunit D3, Non-SMC condensin II complex subunit D3, hCAP-D3, NCAPD3, CAPD3, KIAA0056|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.|
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Provided below are standard protocols that you may find useful for product applications.
Condensin complexes I and II play essential roles inmitotic chromosome assembly and segregation. Both condensinscontain 2 invariant structural maintenance of chromosome (SMC)subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they containdifferent sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMCsubunits that define condensin II (Ono et al., 2003 [PubMed14532007]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Takemoto, A., et al. Nat. Struct. Mol. Biol. 16(12):1302-1308(2009)Lapointe, J., et al. Am. J. Surg. Pathol. 32(2):205-209(2008)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Seshadri, S., et al. BMC Med. Genet. 8 SUPPL 1, S15 (2007) :
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