|Other Names||Pleiotropic regulator 1, PLRG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.|
|Cellular Location||Nucleus. Nucleus speckle.|
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Provided below are standard protocols that you may find useful for product applications.
PLRG1 is necessary for spliceosome assembly and for pre-mRNA splicing.
Lleres, D., et al. EMBO Rep. 11(6):445-451(2010)Dehghan, A., et al. Circ Cardiovasc Genet 2(2):125-133(2009)Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :Andersen, J.S., et al. Nature 433(7021):77-83(2005)Ajuh, P., et al. Nucleic Acids Res. 31(21):6104-6116(2003)
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