|Other Names||Bcl-2-related ovarian killer protein, hBOK, Bcl-2-like protein 9, Bcl2-L-9, BOK, BCL2L9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces apoptosis in a manner dependent on BAX and BAK.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Note=The transmembrane domain is necessary and sufficient for Golgi and ER targeting|
|Tissue Location||Expressed in brain, liver, appendix and lymphoid tissues.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the BCL-2protein family. BCL-2 family members form hetero- or homodimers andact as anti- and pro-apoptotic regulators that are involved in awide variety of cellular activities. This protein contains all fourBCL-2 like domains (BH1, 2, 3 and 4) and is a pro-apoptotic BCL-2protein identified in the ovary.
Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)Ray, J.E., et al. Cell Death Differ. 17(5):846-859(2010)Zhang, H., et al. Int. J. Oncol. 34(4):1135-1138(2009)Rodriguez, J.M., et al. J. Biol. Chem. 281(32):22729-22735(2006)Bartholomeusz, G., et al. Mol. Carcinog. 45(2):73-83(2006)
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