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P2RX1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P51575
Clone Names 100617299
Peptide ID 100617299
Additional Information
Gene ID 5023
Other Names P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, P2RX1, P2X1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name P2RX1
Synonyms P2X1
Function Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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The product of this gene belongs to the family ofpurinoceptors for ATP. This receptor functions as a ligand-gatedion channel with relatively high calcium permeability. Binding toATP mediates synaptic transmission between neurons and from neuronsto smooth muscle, being responsible, for example, for sympatheticvasoconstriction in small arteries, arterioles and vas deferens.Mouse studies suggest that this receptor is essential for normalmale reproductive function. It is possible that the development ofselective antagonists for this receptor may provide an effectivenon-hormonal male contraceptive pill.


Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)Harper, M.T., et al. J. Thromb. Haemost. 8(7):1604-1613(2010)Lalo, U., et al. J. Neurochem. 113(5):1177-1187(2010)Varani, K., et al. Cell. Physiol. Biochem. 25 (2-3), 325-336 (2010) :Corriden, R., et al. Sci Signal 3 (104), RE1 (2010) :

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$ 80.00
Cat# BP16798b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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