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GGPS1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95749 |
|---|---|
| Clone Names | 100617122 |
| Gene ID | 9453 |
|---|---|
| Other Names | Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GGPS1 |
|---|---|
| Function | Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. |
| Cellular Location | Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, myofibril, sarcomere, Z line |
| Tissue Location | Abundantly expressed in testis (PubMed:9741684, PubMed:10026212). Found in other tissues to a lower extent (PubMed:9741684, PubMed:10026212). Expressed in dermal fibroblast and skeletal muscle (PubMed:32403198). |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene is a member of the prenyltransferase family andencodes a protein with geranylgeranyl diphosphate (GGPP) synthaseactivity. The enzyme catalyzes the synthesis of GGPP from farnesyldiphosphate and isopentenyl diphosphate. GGPP is an importantmolecule responsible for the C20-prenylation of proteins and forthe regulation of a nuclear hormone receptor. Alternatetranscriptional splice variants, both protein-coding andnon-protein-coding, have been found for this gene. [provided byRefSeq].
References
Choi, H.J., et al. Yonsei Med. J. 51(2):231-238(2010)Raz, T., et al. Blood 110(6):2102-2109(2007)Miyagi, Y., et al. J. Biochem. 142(3):377-381(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Zhao, Y., et al. Sci. China, C, Life Sci. 43(6):613-622(2000)
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