|Other Names||Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, 251-, (2E, 6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase, GGPS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.|
|Tissue Location||Abundantly expressed in testis. Found in other tissues to a lower extent|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the prenyltransferase family andencodes a protein with geranylgeranyl diphosphate (GGPP) synthaseactivity. The enzyme catalyzes the synthesis of GGPP from farnesyldiphosphate and isopentenyl diphosphate. GGPP is an importantmolecule responsible for the C20-prenylation of proteins and forthe regulation of a nuclear hormone receptor. Alternatetranscriptional splice variants, both protein-coding andnon-protein-coding, have been found for this gene. [provided byRefSeq].
Choi, H.J., et al. Yonsei Med. J. 51(2):231-238(2010)Raz, T., et al. Blood 110(6):2102-2109(2007)Miyagi, Y., et al. J. Biochem. 142(3):377-381(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Zhao, Y., et al. Sci. China, C, Life Sci. 43(6):613-622(2000)
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