|Other Names||RNA-binding protein MEX3B, RING finger and KH domain-containing protein 3, RING finger protein 195, MEX3B, KIAA2009, RKHD3, RNF195|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA2009, RKHD3, RNF195|
|Function||RNA-binding protein. May be involved in post- transcriptional regulatory mechanisms.|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule. Note=Predominantly expressed in the cytoplasm and shuttles between the cytoplasm and the nucleus through the CRM1 export pathway. Localization to P-bodies is dependent on 14-3-3|
|Tissue Location||Highest levels found in fetal brain and testis. Detected in the adult intestinal epithelium, specifically in goblet cell at protein level.|
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RNA-binding protein. May be involved in post-transcriptional regulatory mechanisms.
Nicolas, E., et al. Eur. J. Hum. Genet. 18(10):1107-1113(2010)Willer, C.J., et al. Nat. Genet. 41(1):25-34(2009)Courchet, J., et al. J. Biol. Chem. 283(46):32131-32142(2008)Buchet-Poyau, K., et al. Nucleic Acids Res. 35(4):1289-1300(2007)Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
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