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PIGP Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P57054
Clone Names 100617138
Peptide ID 100617138
Additional Information
Gene ID 51227
Other Names Phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region protein 5, Down syndrome critical region protein C, Phosphatidylinositol-glycan biosynthesis class P protein, PIG-P, PIGP, DCRC, DSCR5, DSCRC
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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This gene encodes an enzyme involved in the first step ofglycosylphosphatidylinositol (GPI)-anchor biosynthesis. TheGPI-anchor is a glycolipid found on many blood cells that serves toanchor proteins to the cell surface. The encoded protein is acomponent of the GPI-N-acetylglucosaminyltransferase complex thatcatalyzes the transfer of N-acetylglucosamine (GlcNAc) fromUDP-GlcNAc to phosphatidylinositol (PI). This gene is located inthe Down Syndrome critical region on chromosome 21 and is acandidate for the pathogenesis of Down syndrome. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Ferrando-Miguel, R., et al. Amino Acids 26(3):255-261(2004)Choi, D.K., et al. Mamm. Genome 12(5):347-351(2001)Kinoshita, T., et al. Curr Opin Chem Biol 4(6):632-638(2000)Watanabe, R., et al. EMBO J. 19(16):4402-4411(2000)

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$ 80.00
Cat# BP16809a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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