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OBFC1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H668
Clone Names 110510041
Peptide ID 110510041
Additional Information
Gene ID 79991
Other Names CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog, OBFC1, STN1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name OBFC1
Synonyms STN1
Function Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Cellular Location Nucleus. Chromosome, telomere.
Research Areas
Citations (0)

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OBFC1 and C17ORF68 (MIM 613129) are subunits of an alphaaccessory factor (AAF) that stimulates the activity of DNApolymerase-alpha-primase (see MIM 176636), the enzyme thatinitiates DNA replication (Casteel et al., 2009 [PubMed 19119139]).OBFC1 also appears to function in a telomere-associated complexwith C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009[PubMed 19854130]).


Levy, D., et al. Proc. Natl. Acad. Sci. U.S.A. 107(20):9293-9298(2010)Miyake, Y., et al. Mol. Cell 36(2):193-206(2009)Wan, M., et al. J. Biol. Chem. 284(39):26725-26731(2009)Casteel, D.E., et al. J. Biol. Chem. 284(9):5807-5818(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)

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$ 80.00
Cat# BP16810b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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