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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   PLEKHF2 Antibody (Center) Blocking Peptide   

PLEKHF2 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9H8W4
Clone Names 110617232
Peptide ID 110617232
Additional Information
Gene ID 79666
Other Names Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2, Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains, EAPF, PH and FYVE domain-containing protein 2, Phafin-2, Phafin2, Zinc finger FYVE domain-containing protein 18, PLEKHF2, ZFYVE18
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ZFYVE18
Function May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis (PubMed:18288467).
Cellular Location Early endosome membrane; Peripheral membrane protein. Endoplasmic reticulum. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots (PubMed:19995552). May translocate to the endoplasmic reticulum in the early phase of apoptosis (PubMed:18288467).
Tissue Location Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells
Research Areas
Citations (0)

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PLEKHF2 (Phafin 2) is a PH and FYVE domain containing protein 2. The FYVE domain and Zinc binding domain targets proteins to membrane lipids via interaction with phosphatidylinositol 3 phosphate, PI3P. The FYVE domain and Zinc binding domain present in Fab1, YOTB, Vac1, and EEA1.


Lin, W.J., et al. Biochem. Biophys. Res. Commun. 391(1):1043-1048(2010)Li, C., et al. J. Mol. Med. 86(4):471-484(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP16820c
Availability: In Stock
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