|Other Names||Septin-11, SEPT11|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria|
|Tissue Location||Widely expressed, except in leukocytes.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
SEPT11 belongs to the conserved septin family offilament-forming cytoskeletal GTPases that are involved in avariety of cellular functions including cytokinesis and vesicletrafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al.,2004 [PubMed 15485874]).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Huang, G.L., et al. World J. Gastroenterol. 16(16):2046-2054(2010)Mostowy, S., et al. J. Biol. Chem. 284(17):11613-11621(2009)Ding, X., et al. Mol. Cells 25(3):385-389(2008)Xin, X., et al. J. Histochem. Cytochem. 55(11):1089-1094(2007)
If you have any additional inquiries please email technical services at email@example.com.