GPHA2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q96T91 |
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Clone Names | 100406009 |
Gene ID | 170589 |
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Other Names | Glycoprotein hormone alpha-2, Putative secreted protein Zsig51, Thyrostimulin subunit alpha, GPHA2, GPA2, ZSIG51 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GPHA2 |
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Synonyms | GPA2, ZSIG51 |
Function | Functions as a heterodimeric glycoprotein hormone with GPHB5 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production (PubMed:12045258). Plays a central role in controlling thyroid cell metabolism (PubMed:12045258). |
Cellular Location | Secreted. |
Tissue Location | Found in a variety of tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GPHA2 is a cystine knot-forming polypeptide and a subunitof the dimeric glycoprotein hormone family (Hsu et al., 2002[PubMed 12089349]).
References
Okajima, Y., et al. Regul. Pept. 148 (1-3), 62-67 (2008) :Suzuki, C., et al. Regul. Pept. 142 (1-2), 60-67 (2007) :Breous, E., et al. Mol. Cell. Endocrinol. 245 (1-2), 169-180 (2005) :Sudo, S., et al. Endocrinology 146(8):3596-3604(2005)Hsu, S.Y., et al. Mol. Endocrinol. 16(7):1538-1551(2002)
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