|Other Names||Glycoprotein hormone alpha-2, Putative secreted protein Zsig51, Thyrostimulin subunit alpha, GPHA2, GPA2, ZSIG51|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Stimulates the thyroid. Binds and activates THSR, leads to increased cAMP production.|
|Tissue Location||Found in a variety of tissues.|
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Provided below are standard protocols that you may find useful for product applications.
GPHA2 is a cystine knot-forming polypeptide and a subunitof the dimeric glycoprotein hormone family (Hsu et al., 2002[PubMed 12089349]).
Okajima, Y., et al. Regul. Pept. 148 (1-3), 62-67 (2008) :Suzuki, C., et al. Regul. Pept. 142 (1-2), 60-67 (2007) :Breous, E., et al. Mol. Cell. Endocrinol. 245 (1-2), 169-180 (2005) :Sudo, S., et al. Endocrinology 146(8):3596-3604(2005)Hsu, S.Y., et al. Mol. Endocrinol. 16(7):1538-1551(2002)
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