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GCNT3 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O95395 |
|---|---|
| Clone Names | 100406227 |
| Gene ID | 9245 |
|---|---|
| Other Names | Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase 3, C2GnT-mucin type, C2GnT-M, hC2GnT-M, Core 2/core 4 beta-1, 6-N-acetylglucosaminyltransferase, C2/4GnT, GCNT3 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GCNT3 |
|---|---|
| Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I- branching enzyme activity by converting linear into branched poly-N- acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Primarily expressed in mucus-secreting tissues. Expressed in colon, kidney, small intestine, trachea, and stomach, where mucin is produced. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of theN-acetylglucosaminyltransferase family. The encoded protein is abeta-6-N-acetylglucosamine-transferase that catalyzes the formationof core 2 and core 4 O-glycans on mucin-type glycoproteins.
References
Tan, S., et al. Am. J. Respir. Cell Mol. Biol. 36(6):737-745(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Huang, M.C., et al. Oncogene 25(23):3267-3276(2006)Beum, P.V., et al. Am. J. Respir. Cell Mol. Biol. 29(1):48-56(2003)Schwientek, T., et al. J. Biol. Chem. 274(8):4504-4512(1999)
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