|Other Names||C-C motif chemokine 7, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, MCP-3, NC28, Small-inducible cytokine A7, CCL7, MCP3, SCYA6, SCYA7|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Synonyms||MCP3, SCYA6, SCYA7|
|Function||Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.|
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This gene encodes monocyte chemotactic protein 3, asecreted chemokine which attracts macrophages during inflammationand metastasis. It is a member of the C-C subfamily of chemokineswhich are characterized by having two adjacent cysteine residues.The protein is an in vivo substrate of matrix metalloproteinase 2,an enzyme which degrades components of the extracellular matrix.This gene is part of a cluster of C-C chemokine family members onchromosome 17q.
McGovern, D.P., et al. Hum. Mol. Genet. 19(17):3468-3476(2010)Han, S., et al. Hum. Immunol. 71(7):727-730(2010)Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :
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