|Other Names||Septin-1, LARP, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24, SEPT1, DIFF6, PNUTL3|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Filament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential).|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis Localizes to the midbody during cytokinesis|
|Tissue Location||Expressed at high levels in lymphoid and hematopoietic tissues.|
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This gene is a member of the septin family of GTPases.Members of this family are required for cytokinesis. This geneencodes a protein associated with the tau-based paired helicalfilament core, and may contribute to the formation ofneurofibrillary tangles in Alzheimer's disease. [provided byRefSeq].
Kato, Y., et al. Int. J. Oncol. 31(5):1021-1028(2007)Steels, J.D., et al. Cell Motil. Cytoskeleton 64(10):794-807(2007)Qi, M., et al. Biochem. Biophys. Res. Commun. 336(3):994-1000(2005)Qi, M., et al. Biochem. Biophys. Res. Commun. 336(3):994-1000(2005)Scanlan, M.J., et al. Cancer Immun. 1, 4 (2001) :
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