SDC4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P31431 |
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Clone Names | 100525125 |
Gene ID | 6385 |
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Other Names | Syndecan-4, SYND4, Amphiglycan, Ryudocan core protein, SDC4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SDC4 (HGNC:10661) |
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Function | Cell surface proteoglycan which regulates exosome biogenesis in concert with SDCBP and PDCD6IP (PubMed:22660413). |
Cellular Location | [Isoform 1]: Membrane; Single-pass type I membrane protein. Secreted. Note=Shedding of the ectodomain produces a soluble form. |
Tissue Location | Detected in fibroblasts (at protein level) (PubMed:36213313, PubMed:1500433). Also expressed in epithelial cells (PubMed:1500433). |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a transmembrane (typeI) heparan sulfate proteoglycan that functions as a receptor inintracellular signaling. The encoded protein is found as ahomodimer and is a member of the syndecan proteoglycan family. Thisgene is found on chromosome 20, while a pseudogene has been foundon chromosome 22.
References
Buhligen, J., et al. J. Cell. Physiol. 225(3):905-914(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Carvallo, L., et al. J. Biol. Chem. 285(38):29546-29555(2010)Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)Hallberg, G., et al. Reprod. Biol. Endocrinol. 8, 35 (2010) :
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