|Other Names||Solute carrier family 2, facilitated glucose transporter member 9, Glucose transporter type 9, GLUT-9, SLC2A9, GLUT9|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate.|
|Cellular Location||Isoform 1: Basolateral cell membrane; Multi- pass membrane protein|
|Tissue Location||Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level).|
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This gene encodes a member of the SLC2A facilitativeglucose transporter family. Members of this family play asignificant role in maintaining glucose homeostasis. The encodedprotein may play a role in the development and survival ofchondrocytes in cartilage matrices. Two transcript variantsencoding distinct isoforms have been identified for this gene.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Facheris, M.F., et al. J. Mol. Neurosci. (2010) In press :Houlihan, L.M., et al. Hum. Mol. Genet. 19(11):2321-2330(2010)Urano, W., et al. Ann. Rheum. Dis. 69(5):932-933(2010)Tabara, Y., et al. Am. J. Nephrol. 32(3):279-286(2010)
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