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MCRS1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q96EZ8
Clone Names 100528088
Peptide ID 100528088
Additional Information
Gene ID 10445
Other Names Microspherule protein 1, 58 kDa microspherule protein, Cell cycle-regulated factor p78, INO80 complex subunit J, MCRS2, MCRS1, INO80Q, MSP58
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MCRS1
Synonyms INO80Q, MSP58
Function Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus (PubMed:11948183). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852). Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity (PubMed:15044100). Binds to G-quadruplex structures in mRNA (PubMed:16571602). Binds to RNA homopolymer poly(G) and poly(U) (PubMed:16571602).
Cellular Location Nucleus. Nucleus, nucleolus Cytoplasm. Note=In microspherules in the nucleolus.
Tissue Location Detected in testis, and at lower levels in spleen, thymus, prostate, uterus, small intestine, colon and leukocytes
Research Areas
Citations (0)

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MCRS1 modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. May be an inhibitor of TERT telomerase activity.


Lin, W., et al. J. Cell. Mol. Med. 13 (11-12), 4608-4622 (2009) :Shi, H., et al. Cancer Sci. 100(9):1585-1590(2009)Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Wu, J.L., et al. BMC Cell Biol. 10, 9 (2009) :Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

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$ 80.00
Cat# BP16872a
Availability: In Stock
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