MOL2B Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86TA1 |
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Clone Names | 91109083 |
Gene ID | 79817 |
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Other Names | MOB kinase activator 3B, Mob1 homolog 2b, Mps one binder kinase activator-like 2B, MOB3B, MOBKL2B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MOB3B (HGNC:23825) |
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Function | Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene shares similarity withthe yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinaseessential for spindle pole body duplication and mitotic checkpointregulation. This gene is located on the opposite strand as theinterferon kappa precursor (IFNK) gene.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010)Davila, S., et al. Genes Immun. 11(3):232-238(2010)Suarez-Gestal, M., et al. Arthritis Res. Ther. 12 (2), R72 (2010) :van Es, M.A., et al. Nat. Genet. 41(10):1083-1087(2009)
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