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SH3BGR Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P55822 |
|---|---|
| Clone Names | 100406106 |
| Gene ID | 6450 |
|---|---|
| Other Names | SH3 domain-binding glutamic acid-rich protein, SH3BGR protein, 21-glutamic acid-rich protein, 21-GARP, SH3BGR |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | SH3BGR |
|---|---|
| Tissue Location | Expressed in heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. SH3 domain binding glutamic acid-rich protein (SH3BGR), also designated 21-glutamic acid-rich protein (21-GARP), is a 239-amino acid protein differentially expressed in heart and skeletal muscle. Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure. SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.
References
Naukkarinen, J., et al. PLoS Genet. 6 (6), E1000976 (2010) :Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :Sandri, C., et al. Hum. Genet. 114(5):517-519(2004)Jiang, L.Q., et al. Hypertens. Res. 25(4):647-652(2002)Scartezzini, P., et al. Hum. Genet. 99(3):387-392(1997)
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